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Gaoping Xiao

Do it just because I really like it

VP, Business Development Syd Labs

19 Erie Drive

Suite 100

Natick, 01760 United States

Phone: 1-617-401-8149 Fax: 1-617-606-5019

E-mail: gpxiao@sydlabs.com Web: www.sydlabs.com

Profile
Summary

Good at:

Streamlining products and services to reduce costs for clients/distributors;
Forming close partnership with suppliers and clients/distributors;
Improving team efficiency to serve clients/distributors better;
Helping small companies grow better and faster with sales increase and investment.

May not the cheapest, but the best quality/price ratio.

Happy if you are happy with our products and services, frustrated if you are frustrated with any of them. Please send your complaint(s) directly to gpxiao@sydlabs.com.

Work Experience

VP, Business Development

Syd Labs, Inc
May, 2010 to Present
Natick, MA USA

Syd Labs, located in Boston, Massachusetts, is dedicated to providing quality products and services for research, development, and manufacturing in academy, industry, and government. In addition to more than 10 000 antibodies, Syd Labs provides more than 1 000 proteins, 300 ELISA kits, and IHC reagents in addition to comprehensive antibody-related services:

Antigen preparation (peptide synthesis, gene synthesis, DNA subcloning, protein expression and purification);
Polyclonal and monoclonal antibody development and screening for antibody applications;
Antibody modification and purification;
Immunoassay and assay development;
Antibody cloning, sequencing, expression, and engineering;
Antibody humanization and affinity maturation;
Stable cell line generation;
Recombinant protein and antibody production from ug to kg scale;
Bio-analytical testing.

Research Fellow

Yale University
March, 2007 to August, 2009
New Haven, CT USA

Published 4 scientific papers.

Research Fellow

Harvard Medical School
May, 2003 to February, 2007
Boston, MA USA

Prepared a part of a RO1 research grant proposal to NIH, which got approved;
Published 6 scientific papers and 1 patent pending;
Gave 2 poster presentations on the 2004 General meeting of American Society of Microbiology;
Cooperated with two research groups at University of Chicago and INRS in Canada, respectively, to work on different scientific projects.

Education

University of California, Los Angeles

Ph.D. | Microbiology and Molecular Genetics
September, 1997 to December, 2002

Published 2 scientific papers;
Gave a poster presentation on the 2001 General meeting of American Society of Microbiology

Shanghai Institute of Plant Physiology

Master's Degree | Plant Physiology
August, 1994 to June, 1997

Studied flower development.

Wuhan University

Bachelor's Degree | Biochemistry
September, 1990 to July, 1994

Basic training in biological sciences, especially biochemistry.

Training

AIG

Course Insurance
1994 to 1994
Pudong, Shanghai China

How to sell insurance package.

Publications

Morpholino oligonucleotides do not participate perfectly in standard Watson-Crick complexes with RNA

http://www.ncbi.nlm.nih.gov/pubmed/20817753
2010
Xiao G, Wesolowski D, Izadjoo M, Altman S.

RNase P from E. coli will cleave a RNA at a site designated in a complex with an external guide sequence (EGS). The location of the site is determined by the Watson-Crick complementary sequence that can be formed between the RNA and the EGS. Morpholino oligonucleotides (PMOs) that have the same base sequences as any particular EGS will not direct cleavage by RNase P of the target RNA at the expected site in three mRNAs. Instead, cleavage occurs at a secondary site that does not correspond exactly to the expected Watson-Crick sequence in the PMO. This cleavage in the mRNA for a drug resistance gene, CAT mRNA, is at least second order in the concentration of the PMOs, but the mechanism is not understood yet and might be more complicated than a simple second-order reaction. EGSs and PMOs inhibit the reactions of each other effectively in a competitive fashion. A basic peptide attached to the PMO (PPMO) is more effective because of its binding properties to the mRNA as a substrate. However, a PMO is just as efficient as a PPMO on a mRNA that is mutated so that the canonical W-C site has been altered. The altered mRNA is not recognizable by effective extensive W-C pairing to an EGS or PMO. The complex of a PMO on a mutated mRNA as a substrate shows that the dimensions of the modified oligonucleotide cannot be the same as a naked piece of single-stranded RNA.

Patents

Methods for identifying candidate compounds for treating, reducing, or preventing pathogenic infections

Application WO/2005/069989
Rahme, L., Déziel, E., Lépine, F., Tompkins, R.G., Xiao, G.
September 8, 2006

Disclosed are methods for identifying candidate compounds for treating, reducing, or preventing a pathogenic infection, the methods including: (a) contacting a pathogenic cell with a candidate compound; and (b) measuring the production of a molecule selected from the group consisting of an 4-hydroxy-2-alkylquinoline (HAQ) molecule, 4-hydroxy-2-heptylquinoline (HHQ) molecule, or a derivative or precursor thereof in the cell, a candidate compound that reduces the production relative to production of the molecule by a cell not contacted with the candidate compound, identifying a candidate compound useful for treating, reducing, or preventing a pathogenic infection.

Organizations

SAPA-NE

Member
2009 to 2014
Boston, MA USA

Sino-American Pharmaceutical Professionals Association (SAPA) is a major US not-for-profit organization for pharmaceutical professionals with Chinese-heritage. Founded in 1993 and headquartered in the NJ/NY/CT tri-state area, SAPA grew rapidly and has become one of the most active and well-recognized Chinese-heritage enduring professional organizations in the United States. SAPA is an independent, not-for-profit organization with nearly 4000 members in USA, Mainland China, Hong Kong, Taiwan and Japan united by a commitment to promoting pharmaceutical science and technology and their essential roles in fostering member's career development.

SAPA's New England Chapter, SAPA-NE, aims to promote pharmaceutical exchanges and cooperation in both industry and academia between China and the USA and to assist career opportunities and development for our members in New England area. SAPA-NE currently has more than 900 members, most have advanced degrees. SAPA publishes "SAPA Newsletter", organizes the annual conferences, and seminars/symposia on specific topics of scientific, technological, and professional development, hosts or co-hosts pharmaceutical forum in US and China.

Languages

Chinese

Native or Bilingual

English

Fluent
Public Information

Syd Labs, Inc

Syd Labs, located in Boston, Massachusetts, is dedicated to providing quality products and services for research and development in academy, industry, and government. We know how important quality is for your work and price for your business.

We have always tried our best to let you, our valuable customers and partners, save money and work better.

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My profile on LinkedIn in English, including summary, experience, education, language, skills and endorsement.
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